| script | guión |
| Script department | Dramaturgia |
| Scripting programming language | Lenguaje interpretado |
| scriptural | bíblico |
| Scripture | Biblia |
| Scriptures | Biblia |
| scriptwriter | guionista |
| scrivener | escribano |
| scrofula | escrófula |
| scroll | desfilar |
| scroll bar | barra de desplazamiento |
| scrollbar | barra de desplazamiento |
| scrooge | avaro |
| Scrooge McDuck | Rico McPato |
| Scrophularia | Scrophularia |
| Scrophularia nodosa | Scrophularia nodosa |
| Scrophulariaceae | Scrophulariaceae |
| scrotal | escrotal |
| scrotum | escroto |
| Scrotums | Escroto |
| scrounge | gorronear |
| scrounger | ladron |
| Scrovegni Chapel | Capilla de los Scrovegni |
| scrub | fregar |
| scrub brush | cepillo de fregar |
| Scrub Island | Isla Scrub |
| scrubbers | acepillar |
| scrubby | arrastrado |
| scruff | desaseado |
| scruffy | sucio |
| scrum | melée |
| scrummage | melée |
| scrumptious | delicioso |
| scruple | remordimiento |
| scruples | escrupulo |
| scrupulosity | reflexionar |
| scrupulous | concienzudo |
| scrupulously | cuidadosamente |
| scrupulousness | reflexionar |
| scruter | explorar |
| scrutinize | explorar |
| scrutiny | escrutinio |
| Scrying | Crystal Ball |
| SCSI | Small Computer System Interface |
| scuba | escafandra autónoma |
| scuba dive | bucear con escafandra autónoma |
| scuba diver | buceador |
| scuba diving | buceo |
| Scuderia Ferrari | Scuderia Ferrari |
| Scuderia Toro Rosso | Scuderia Toro Rosso-Ferrari |
| scuff | desgaste |
| scuffle | batalla |
| scullery | fregadero |
| sculpin | coto |
| sculpt | labrar |
| sculptor | escultor |
| Sculptor Dwarf Galaxy | Sculptor |
| sculptress | tallista |
| sculptural | escultural |
| sculpture | labrar |
| scum | escoria |
| SCUMM | SCUMM |
| scummy | espumoso |
| Scuol | Scuol |
| scurf | caspa |
| scurfy | casposo |
| Scurillous | Bajo |
| Scurillously | Bajo |
| scurries | precipitacion |
| scurrility | ascosidad |
| scurrilous | vulgar |
| scurry | escurrirse |
| scurvily | vil |
| scurvy | escorbuto |
| Scutari | Lago Skadar |
| scutcheon | escudo de armas |
| Scutellaria | Scutellaria |
| Scutellaria galericulata | Scutellaria galericulata |
| Scutellosaurus | Scutellosaurus |
| Scutosaurus | Scutosaurus |
| scuttle | arruinar |
| scuttle away | escabullirse |
| scuttle off | escabullirse |
| scuttles | arruinado |
| Scutum | Scutum |
| Scylax of Caryanda | Escílax de Carianda |
| Scyliorhinus | Scyliorhinus |
| Scylla | Escila |
| Scylla and Charybdis | Escila y Caribdis |
| Scyphozoa | Scyphozoa |
| scythe | guadaña |
| Scythia | Escitia |
| Scythian | Escitia |
| Scythians | Escitia |
| SD | SD |
| SD Compostela | Sociedad Deportiva Compostela |
| SD Eibar | Sociedad Deportiva Eibar |
| SD Eivissa | Unión Deportiva Ibiza Eivissa |
| SD Huesca | Sociedad Deportiva Huesca |
| SD Lemona | Sociedad Deportiva Lemona |
| SD Negreira | Sociedad Deportiva Negreira |
| SD Ponferradina | Sociedad Deportiva Ponferradina |
| Sderot | Sederot |
| SDR SDRAM | SDRAM |
| SDRAM | SDRAM |
| SE | IT |
