| simpleness | sencillez |
| simpleton | estúpido |
| Simplex algorithm | Algoritmo simplex |
| Simplicial complex | Complejo simplicial |
| Simplicissimus | Simplicissimus |
| simplicity | sencillez |
| simplification | simplificación |
| Simplified Chinese | chino simplificado |
| Simplified Chinese character | Simplificación de los caracteres chinos |
| Simplified English | Inglés simple |
| Simplified Latin | interlingua |
| Simplified molecular input line entry specification | SMILES |
| simplify | simplificar |
| simplistic | simplista |
| simply | sólo |
| Simply Red | Simply Red |
| Simpson family | Bart Simpson |
| Simpsons Roasting on an Open Fire | Especial de Navidad de los Simpsons |
| Simrishamn | Simrishamn |
| Simrishamn Municipality | Simrishamn |
| Simson line | Recta de Simson |
| Simtex | Simtex |
| simulacrum | simulacro |
| simular | parejo |
| simulate | aparentar |
| simulated | simulado |
| simulation | imitación |
| simulator | simulador |
| simultaneity | simultaneidad |
| simultaneous | simultáneo |
| simultaneously | al mismo tiempo |
| simultaneousness | simultaneidad |
| Simutrans Transport Simulator | Simutrans |
| Simão Sabrosa | Simão Sabrosa |
| Siméon Denis Poisson | Siméon Denis Poisson |
| Simón Bolívar | Simón Bolívar |
| Simón Bolívar International Airport | Aeropuerto Internacional de Maiquetía Simón Bolívar |
| Simón de Roxas Clemente y Rubio | Simón de Rojas Clemente y Rubio |
| Simón Iturri Patiño | Simón Iturri Patiño |
| sin | pecado |
| Sin After Sin | Sin After Sin |
| Sin City | Sin City |
| Sinai | Sinaí |
| Sinai and Palestine Campaign | Campaña de Palestina y Sinaí |
| Sinai Peninsula | Sinaí |
| Sinaloa | Sinaloa |
| Sinaloa de Leyva | Sinaloa de Leyva |
| Sinaloan Crow | Corvus sinaloae |
| SINALTRAINAL | SINALTRAINAL |
| Sinan | Sinan |
| Sinanthropus | Hombre de Pekín |
| Sinapis | Sinapis |
| Sinarcas | Sinarcas |
| Sinatra Doctrine | Doctrina Sinatra |
| Sinbad the Sailor | Simbad |
| Sinc filter | Filtro sinc |
| since | como |
| since then | desde |
| Sincelejo | Sincelejo |
| sincere | honrado |
| sincerely | verdaderamente |
